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Nonalcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: A Coexisting Challenge

  1. Mr. Avhilash Mishra, MBBS, Student Ram Krishna Medical College, Bhopal

  2. Dr. Satrudhan Kanta, Assistant Professor, Department of Biochemistry, Ram Krishna Medical College, Bhopal (Corresponding Author)


2024, July, Volume 1 Issue 1, P 16- 21




Abstract:

Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) are increasingly recognized as coexisting challenges, with a strong link between them. This growing epidemic poses a significant threat to global health. This review explores the shared risk factors and pathophysiological mechanisms underlying both NAFLD and T2DM, highlighting the role of insulin resistance and dyslipidemia. We discuss the potential complications associated with their coexistence, including an increased risk of advanced liver disease and cardiovascular events. Furthermore, the underdiagnosis of NAFLD in T2DM patients is addressed. By improving our understanding of this complex relationship, we can develop more effective strategies for managing these conditions and improving patient outcomes.

 

Keywords: nonalcoholic fatty liver disease, type 2 diabetes mellitus, Cirrhosis, insulin resistance, metabolic syndrome,

 

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