Bariatric Surgery: A Potential Option for Severe NAFLD/NASH

1. Dr. Swati Arora, Associate Professor, Department of Biochemistry, Al Karim University

2. Dr. Amla Paul, Assistant Professor, Department of Surgery, RKD Medical C. H., Bhopal (Corresponding Author)

2024, July, Volume 1 Issue 1, P 28- 33

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Abstract:

Bariatric surgery has emerged as a promising therapeutic option for patients with severe nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) unresponsive to conventional treatments. This review explores the efficacy and mechanisms of bariatric surgery in addressing NAFLD/NASH. By inducing significant weight loss and metabolic improvements, bariatric surgery has been shown to reverse steatosis, reduce inflammation, and potentially improve fibrosis. Additionally, the surgery has a positive impact on associated comorbidities such as type 2 diabetes, hypertension, and dyslipidemia. While promising, further long-term studies are needed to fully establish the long-term benefits and identify optimal patient selection criteria for bariatric surgery in the management of NAFLD/NASH.

Keywords: bariatric surgery, NAFLD, NASH, obesity, metabolic syndrome