Epidemiology of Congenital Musculoskeletal Malformations in Perinates.
- rpihefngo
- Jun 19, 2024
- 2 min read
Updated: Apr 18
2024, Volume 1, Issue 1, Page: 34-38
Dr. Dilip Kumar Bhimrao Kolekar, Professor & HOD, Department of Anatomy, Ram Krishna Medical College Hospital and Research Centre, Bhopal
Dr. Abhimanu Kumar, Post-Doctoral, DSc Medical Anatomy (Scholar), Faculty of Medical Sciences, Manipur International University, Imphal, Manipur, India.
Abstract:
Background: Congenital malformations, arising from disruptions in organogenesis before birth, can manifest as the absence or altered configuration of anatomical structures. Understanding the prevalence of these conditions is crucial for establishing effective prevention programs. This study aimed to determine the frequency and patterns of congenital malformations specifically affecting the musculoskeletal system in both liveborn and stillborn perinates.
Methods: A prospective observational study was conducted at the Department of Anatomy & Obstetrics and Gynecology, RKMC, BHOPAL, from July 2023 to June 2024. All liveborn and stillborn infants with identified congenital malformations were included. Detailed physical examinations were performed, and epidemiological data were collected from parents using a pre-tested structured proforma.
Results: Among 7985 total births during the study period, 38 cases of congenital malformations were identified. The overall prevalence of congenital malformations was found to be 0.48% (38/7985), with a higher proportion observed in stillbirths (31 cases, 81.58%) compared to live births (7 cases, 18.42%). Musculoskeletal system involvement was noted in 8 cases (21.05% of all malformations). The most frequent musculoskeletal malformations were congenital talipes equinovarus (CTEV) and polydactyly, followed by rudimentary forearm and one case of achondroplasia. Notably, central nervous system anomalies were often associated with musculoskeletal system malformations in the observed cases.
Conclusion: This study provides valuable data on the prevalence and patterns of congenital musculoskeletal malformations in the perinatal population of this region. The findings underscore the need for targeted strategies for the prevention, early diagnosis, and timely management of these conditions. Further research with a larger sample size and detailed etiological investigations is warranted.
Key Words: Congenital talipes equinovarus (CTEV), polydactyly, achondroplasia, musculoskeletal malformations, perinatal, prevalence, stillbirth.